MULTIPLE CONSERVED CELL ADHESION PROTEIN INTERACTIONS MEDIATE NEURAL WIRING OF A SENSORY CIRCUIT IN C. ELEGANS

Multiple conserved cell adhesion protein interactions mediate neural wiring of a sensory circuit in C. elegans

Nervous system function relies on precise synaptic connections.A number of widely-conserved cell adhesion proteins are implicated in cell recognition between synaptic Filament partners, but how these proteins act as a group to specify a complex neural network is poorly understood.Taking advantage of known connectivity in C.elegans, we identified an

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WIM calibration and data quality management

Weigh-in-motion (WIM) scales are installed on various higher order roads in South Africa to provide traffic loading information for pavement design, strategic planning and law enforcement.Some WIM systems produce anomalies that cannot be satisfactorily explained even by highly experienced professionals.Much of the problem relates to the difficulty

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Developing a post-myocardial infarction medicines optimisation clinic: core competencies for upskilling pharmacists and initial patient feedback

Background Medicines optimisation and adherence support are essential to secondary prevention after myocardial infarction (MI).Following successful implementation of a consultant pharmacist-led post-MI medicines optimisation clinic, the service was expanded by training advanced clinical pharmacists to manage clinics (with appropriate multidisciplin

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